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While C677T and A1298C do decrease enzyme activity and make MTHFR function suboptimal, carriers can generally expect to have no trouble converting enough homocysteine to methionine
doi: 10.1016/j.ejim.2010.05.007, 18
Patients and clinicians should verify the current status with the MHRA and EMA, as the regulatory position may change
CO-50 (medical necessity not met) fires when the payer determines the service wasn't medically necessary based on the submitted diagnosis
Many patients experience significant weight loss within the first few weeks of therapy
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